Veterinary OTC

[Veterinary Drug Name]

Generic name: Albendazole Granules

Trade name: Achongqing

English name: Albendazole Granules

Pinyin: Abendazuo Keli

[Main Ingredients] Albendazole

[Description] This drug is of off-white granules.

[Pharmacological Action] Benzimidazole anthelmintic. Albendazole has a broad-spectrum anthelmintic effect, effective against nematodes, tapeworms, and trematodes, but ineffective against schistosomes. The mechanism of action of albendazole primarily involves binding to the tubulin of sensitive parasites, preventing the polymerization and assembly of α-tubulin into microtubules, thereby affecting the processes of mitosis, protein assembly, and energy metabolism in the cells of the parasites.

Albendazole is well absorbed after oral administration and is rapidly metabolized in the body to sulfoxide (the main active metabolite for anthelmintic action) and sulfone. Within 20 hours after administration, the plasma drug peak concentration of the metabolites albendazole sulfoxide and albendazole sulfone are reached. The half life of the sulfoxide metabolite in cattle, sheep, pigs, and chickens are 20.5, 7.7-9.0, 5.9, and 4.3 hours, respectively, and the half life of the sulfone metabolite in cattle, sheep, pigs, and chickens are 11.6, 11.8, 9.2, and 2.5 hours, respectively.

[Function and Use] Anthelmintic, for the treatment of nematodiasis, cestodiasis, and trematodiasis in livestock and poultry.

[Dosage and Administration] On the basis of this drug. Oral administration: 50-100mg/time per 1kg of body weight for horses, 100-150mg/time per 1kg of body weight for cattle and sheep; 50-100mg/time per 1kg of body weight for pigs, 250-500mg/time per 1kg of body weight for dogs, and 100-200mg/time per 1kg of body weight for poultry.

[Adverse Reaction] (1) Dogs receiving albendazole at a dose of 50 mg/kg twice daily may gradually develop anorexia.

(2) It is prohibited during lactation period.

(3) Use of albendazole in early pregnancy in sheep, rabbits, and other animals may be associated with teratogenic and embryotoxic effects.

[Precautions] Administration with caution within the first 45 days of pregnancy in animals.

[Withdrawal Period] 14 days for cattle, 4 days for sheep, 7 days for pigs, and 4 days for poultry; 60 hours for the weaning period.

[Specification] 10%

[Package] 1000g/bag × 20bags/carton

[Storage] It should be tightly sealed for storage.

[Shelf Life] 2 years

[Production License No.] (2022) SYSCZZ No. 08019

[GMP Certificate No.] (2022) SY GMP ZZ No. 08010

[Approval No.] SYZ No. 080196246

[Executive Standard] Chemical Drug Volume of Veterinary Drug Quality Standard (2017 Edition)