Veterinary OTC

[Veterinary Drug Name]

Generic name: Fenbendazole Granules

Trade name: Weishikang

English name: Fenbendazole Granules

Pinyin: Fenbendazuo Keli

[Main Ingredients] Fenbendazole

[Description] This drug is of off-white granules.

[Pharmacological Action] Anthelmintic. Fenbendazole exhibits a wide range of activity against helminths such as nematodes, tapeworms, and trematodes, but it does not work against schistosomes. Its mode of action involves binding to tubulin proteins in susceptible worms, which inhibits their ability to polymerize with α-tubulin and form microtubules. This interference disrupts essential cellular processes in the worms, including mitosis, protein assembly, and energy metabolism, thereby impeding their reproduction.

After fenbendazole is administered orally, only a little of it be absorbed. It is absorbed slowly by ruminants and slightly faster by monogastric animals. The blood concentration peaking time is 24 hours for dogs and 2-3 days for sheep. The absorbed fenbendazole is metabolized into sulfoxide (active orfendazole) and sulphone. For cattle, sheep and pigs, 44%-50% of fenbendazole is excreted in its original form in feces and less than 1% is excreted in urine.

[Function and Use] Anthelmintic, for the treatment of nematodosis and teniasis.

[Dosage and Administration] On the basis of this drug. Oral administration: 50-75 mg/time per 1kg of body weight for horses, cattle, sheep and pigs; 50-500mg/time per 1kg of body weight for dogs and cats; 0.1-0.5g/time per 1kg of body weight for poultry.

[Adverse Reaction] Occasionally, dogs and cats may experience vomiting when given the drug orally.

[Precautions] Resistance to this product may emerge in sensitive parasites, potentially leading to cross-resistance with other benzimidazoles.

[Withdrawal Period] 14 days for cattle and sheep, 3 days for pigs and 28 days for poultry; 7 days for the weaning period.

[Specification] 10%

[Package] 1000g/bag × 20bags/carton

[Storage] It should be tightly sealed for storage.

[Shelf Life] 2 years

[Production License No.] (2022) SYSCZZ No. 08019

[GMP Certificate No.] (2022) SY GMP ZZ No. 08010

[Approval No.] SYZ No. 080196248

[Executive Standard] Chemical Drug Volume of Veterinary Drug Quality Standard (2017 Edition)