Veterinary Rx

[Veterinary Drug Name]

Generic name: Kitasamycin  Tartrate  Soluble  Powder

Trade name: Jiluoer

English name: Kitasamycin Tartrate Soluble Powder

Pinyin: Jiushisuan Jitameisu Kerongxingfen

[Main Ingredients] Kitasamycin

[Description] This drug is of white or off-white powder.

[Pharmacological Action] Pharmacodynamics: Kitasamycin is a macrolide antibacterial drug. Its antibacterial spectrum is similar to that of erythromycin, and its mechanism of action is the same as that of erythromycin. Sensitive Gram-positive bacteria include Staphylococcus aureus (including penicillin resistant Staphylococcus aureus), Streptococcus pneumoniae, Streptococcus, Bacillus anthracis, Erysipelothrix rhusiopathiae, Listeria monocytogenes, Clostridium putrefaciens, Clostridium emphysematous, etc. sensitive Gram-negative bacteria include Haemophilus influenzae, Neisseria meningitidis, Pasteurella, etc. In addition, it also has a good effect on mycoplasma. The antibacterial effect on most Gram-positive bacteria is slightly inferior to erythromycin, the antibacterial effect on mycoplasma is similar to tylosin, and it is also effective on some Gram-negative bacteria, rickettsia and spirochetes, and the effect on drug-resistant Staphylococcus aureus is better than erythromycin and tetracycline.

Pharmacokinetics: Oral administration results in good absorption, reaching peak plasma concentration within 2 hours. The drug is widely distributed throughout major organs, with higher concentrations found in liver, lung, kidney, and muscle tissues, often exceeding blood levels. Excretion primarily occurs via the hepatobiliary system, with high concentrations in bile and feces. A small amount is excreted through the kidneys.

[Drug Interaction] (1) It is inappropriate to be used simultaneously with other macrolides, lincosamides, and amide alcohols due to the same target site of action.

(2) When used together with β-lactams, it exhibits an antagonistic effect.

[Function and Use] Macrolide antibiotic, primarily for the treatment of infections caused by Gram-positive bacteria, mycoplasmas, etc.

[Dosage and Administration] On the basis of this drug. Mixed drinking: 2.5-5g per 1L of water for chickens, administered for 3-5 consecutive days.

[Adverse Reaction] After oral administration, animals may experience dose-dependent gastrointestinal disturbances (such as vomiting, diarrhea, intestinal pain, etc.), which occur at a lower rate compared to erythromycin.

[Precautions] This drug cannot be used for hens laying eggs for human consumption during the laying period.

[Withdrawal Period] 7 days for chickens.

[Specification] 100g: 10g (10,000,000 units)

[Package] 100g/packet × 10 packets/box × 8 boxes/carton

[Storage] It should be tightly sealed in a dry place for storage.

[Shelf Life] 2 years

[Production License No.] (2022) SYSCZZ No. 08019

[GMP Certificate No.] (2022) SY GMP ZZ No. 08010

[Approval No.] SYZ No. 080192730

[Executive Standard] Volume I of Veterinary Pharmacopoeia of the People’s Republic of China (2020 Edition)