Veterinary Rx

[Veterinary Drug Name]

Generic name: Tylosin Tartrate Soluble Powder

Trade name:

English name: Tylosin Tartrate Soluble Powder

Pinyin: Jiushisuan Tailejunsu Kerongxingfen

[Main Ingredients] Tylosin

[Description] This drug is of white to pale yellow powder.

[Pharmacological Action] Pharmacodynamics: Tylosin is a macrolide antibiotic specifically used in animals and exhibits strong activity against mycoplasma. Its antibacterial spectrum is similar to erythromycin, including sensitive Gram-positive bacteria such as Staphylococcus aureus (including penicillin-resistant Staphylococcus aureus), Streptococcus pneumoniae, Streptococcus, Bacillus anthracis, Erysipelothrix rhusiopathiae, Listeria monocytogenes, Clostridium perfringens, and Clostridium emphysematous. Sensitive Gram-negative bacteria include Haemophilus, Neisseria meningitidis, and Pasteurella. Bacteria can develop resistance to this drug, and there is partial cross-resistance between Staphylococcus aureus and erythromycin.

Pharmacokinetics: Tylosin is absorbed from the gastrointestinal tract after oral administration, whereas tylosin phosphate is less absorbed. Once absorbed, tylosin distributes widely within the body. Organ concentrations following injection are 2-3 times higher than those after oral administration but do not easily penetrate cerebrospinal fluid.

[Drug Interaction] (1) It is inappropriate to be used simultaneously with other macrolides, lincosamides, and amide alcohols due to the same target site of action.

(2) When used together with β-lactams, it exhibits an antagonistic effect.

[Function and Use] Macrolide antibiotic, for the treatment of Gram-positive bacterial and Mycoplasma infections in poultry.

[Dosage and Administration] On the basis of this drug. Mixed drinking: 1g per 1L of water for poultry, administered for 3-5 consecutive days.

[Adverse Reaction] No adverse reactions have been observed with the proper use of the recommended dosage and administration.

[Precautions] This drug cannot be used for hens laying eggs for human consumption during the laying period.

[Withdrawal Period] 1 day for chickens.

[Specification] 100g: 50g (50,000,000 units)

[Package] 100g/packet × 10 packets/box × 8 boxes/carton

[Storage] It should be tightly sealed and kept in a dry place for storage.

[Shelf Life] 2 years

[Production License No.] (2022) SYSCZZ No. 08019

[GMP Certificate No.] (2022) SY GMP ZZ No. 08010

[Approval No.] SYZ No. 080192733

[Executive Standard] Volume I of Veterinary Pharmacopoeia of the People’s Republic of China (2020 Edition)